(CF3CO)2O/CF3SO3H-mediated synthesis of 1,3-diketones from carboxylic acids and aromatic ketones

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(CF3CO)2O/CF3SO3H-mediated synthesis of 1,3-diketones from carboxylic acids and aromatic ketones

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One of the most common reactions in chemistry is the synthesis of ketones from acids1−4. First, the acid is changed into its chloride. Then the acid chloride reacts with an organometallic reagent or gives a FriedelCrafts type reaction in the presence of Lewis acids. These methods are very useful for most aliphatic acid halides and good yields can be obtained in this way. However, if this method...

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ژورنال

عنوان ژورنال: Beilstein Journal of Organic Chemistry

سال: 2014

ISSN: 1860-5397

DOI: 10.3762/bjoc.10.236